研究内容

投稿論文

1996年4月~2002年3月 東京大学大学院薬学系研究科 生体分析化学教室

ここでは,自分が中心になって研究した論文を紹介します.少しずつではありますが,それぞれの研究を論文にするまでの裏話についても紹介したいと思います.

8 蛍光性ベンゾフラザン試薬の総説です

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton
Seiichi Uchiyama, Tomofumi Santa, Natsuko Okiyama, Takeshi Fukushima, Kazuhiro Imai
Biomed. Chromatogr., 2001, 15, 295-318
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7

A fluorogenic reagent, 4-mercapto-7-methylthio-2,1,3-benzoxadiazole for carboxylic acids, designed by prediction of the fluorescence intensity 4-sulfamoyl-7-aminobenzofurazan
Seiichi Uchiyama, Tomofumi Santa, Kazuhiro Imai
Anal. Chem., 2001, 73, 2165-2170
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6

Study on the fluorescent "on-off" properties of benzofurazan compounds bearing an aromatic substituent group and design of fluorescent "on-off" derivatization reagents
Seiichi Uchiyama, Tomofumi Santa, Kazuhiro Imai
Analyst, 2000, 125, 1839-1845
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5

Semi-empirical PM3 calculations predict the fluorescence quantum yields of 4-monosubstituted benzofurazan compounds
Seiichi Uchiyama, Tomofumi Santa, Natsuko Okiyama, Kentaro Aduma, Kazuhiro Imai
J. Chem. Soc., Perkin Trans. 2, 2000, 1199-1207
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4

A fluorogenic reagent, 7-phenylsulfonyl-4-(2,1,3-benzoxadiazolyl) isocyanate for alcohols, with development based on the empirical method for prediction
Seiichi Uchiyama, Tomofumi Santa, Sachiko Suzuki, Hirochika Yokosu, Kazuhiro Imai
Anal. Chem., 1999, 71, 5367-5371
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3

Fluorescence characteristics of six 4,7-disubstituted benzofurazan compounds: an experimental and semi-empirical MO study
Seiichi Uchiyama, Tomofumi Santa, Kazuhiro Imai
J. Chem. Soc., Perkin Trans. 2, 1999, 2525-2532
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2

Semi-empirical PM3 calculation reveals the relationship between the fluorescence characteristics of 4,7-disubstituted benzofurazan compounds, the LUMO energy and the dipole moment directed from the 4- to the 7-positions
Seiichi Uchiyama, Tomofumi Santa, Kazuhiro Imai
J. Chem. Soc., Perkin Trans. 2, 1999, 569-576
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1 懐かしの第一報です

Effects of the substituent groups at the 4- and 7-positions on the fluorescence characteristics of benzofurazan compounds
Seiichi Uchiyama, Tomofumi Santa, Takeshi Fukushima, Hiroshi Homma, Kazuhiro Imai
J. Chem. Soc., Perkin Trans. 2, 1998, 2165-2173